Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of PDK2 in mouse tissue homogenates, cell lysates, cell culture supernates.
Target Information: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]